Ukusetyenziswa kwezicatshulwa zezityalo kwisondlo sezilwanyana: amandla aguqula impilo yendalo
Ukususela oko i-EU yavala ngokupheleleyo ukusetyenziswa kwee-antibiotics njengezikhuthazi zokukhula ngo-2006, imfuno yehlabathi yezinye iindlela iye yaba yinto engxamisekileyo ngakumbi. Ukusuka ekufuyeni imfuyo kunye neenkukhu ukuya kulawulo lwempilo yezilwanyana zasekhaya, izicatshulwa zezityalo ziye zavela njengohlobo lwezongezo zokutya ezisebenzayo, ezikhuselekileyo, ezizinzileyo, nezilawulekayo, ezibonelela ngesisombululo esiluhlaza nesizinzileyo sokufuya izilwanyana zanamhlanje ngenxa yeempawu zazo zeziphumo ezingezizo ezilungileyo, ukunganyangeki ngamayeza amaninzi, kunye nentsalela ephantsi.
Iintlobo eziphambili kunye nezithako ezisebenzayo zeZithako zeZityalo
Izicatshulwa zezityalo zingahlulwa ngokwenkqubo yomthombo, ukwakheka kunye nenkqubo yokukhupha:
● Ngokwenxalenye yesityalo: iiRhizomes (umz. iAstragalus, iGlycyrrhiza), amagqabi (umz. iTi, iRosemary), iziqhamo (umz. iCitrus, imbewu yeediliya), izityalo ezipheleleyo (umz. iEchinacea, iMint).
● Ngokwezithako ezikhutshiweyo: iipolyphenols (iiflavonoids, iitannins), iiterpenoids (iioyile ezibalulekileyo, iisaponins), iialkaloids (iberberine, ipiperine), iipolysaccharides (ii-astragalus polysaccharides, iilentinuns polysaccharides).
● Ngokwendlela yokunyibilika: izicatshulwa ezinyibilikayo emanzini (iipolysaccharides, iipolyphenols), izicatshulwa ezinyibilikayo zamafutha (iioyile ezibalulekileyo, ii-pigment).
Izinto ezisebenzayo eziphambili kunye nemisebenzi yazo:
● Iipolyphenols: iipolyphenols zeti (i-antioxidant), ii-soy isoflavones (ii-prebiotics), iiProanthocyanidins (ezilwa nokuvuvukala).
● Ioyile eguquguqukayo: i-thymol (i-antimicrobial), i-carvacrol (i-growth promoter), i-eucalyptol (impilo yokuphefumla).
● IiPolysaccharides: i-β-glucan (ukuvuselela amasosha omzimba), ii-fructooligosaccharides (isenzo se-prebiotic), i-mannan oligosaccharide (i-pathogen adsorption).
Imisebenzi Ephambili kunye Neziphumo Zezicatshulwa Zezityalo Ekutyeni Kwezilwanyana
● Ilwa neentsholongwane, ilwa nokudumba kunye nokuphucula amajoni omzimba
Izicatshulwa zezityalo zifumana iziphumo ezinobungozi obuphantsi okanye ezingezizo iintsholongwane ngokuphazamisa ii-membrane zeseli zebhaktheriya, ukuthintela umsebenzi we-enzyme, okanye ukuphazamisa imetabolism yeentsholongwane ezibangela izifo. Umzekelo, isicatshulwa seStephania sinokuthintela i-β-lactamase kunye ne-Staphylococcus aureus, egqwesileyo kune-ampicillin; Isicatshulwa segalikhi sithintela i-endometritis ngokuthintela iintsholongwane zesibeleko. Kwintsimi yezilwanyana zasekhaya, isicatshulwa seziqhamo seMonk sinokunciphisa ukwenziwa kwezinto ezibangela ukudumba, ngelixa ioyile ye-Oregano edityaniswe nee-antibiotics iphucula kakhulu izinga lokunyanga i-escherichia coli. Ukongeza, ii-polysaccharides zezityalo (umz., ii-astragalus polysaccharides) zonyusa kakhulu amandla omzimba okuzikhusela ngokwenza ii-macrophages kunye nokukhuthaza ukwanda kwee-lymphocytes ze-T/B.
● Ukuthintela ukuxinana kwe-oxidation kunye nokuthintela uxinzelelo
Iiflavonoids kunye neepolyphenols kwizityalo ezikhutshwayo zikhusela iiseli ekonakaleni kwe-oxidative ngokukhupha ii-free radicals kunye nokunciphisa i-lipid peroxidation. Umzekelo, ii-tea polyphenols kunye nee-proanthocyanidins zinokuphucula umsebenzi we-superoxide dismutase (SOD) kunye ne-catalase (CAT), zinciphise iintlobo ze-reactive oxygen. Kwizifundo eziqhutywe kwizinja zezilwanyana zasekhaya, ii-green tea polyphenols zithintele ukwahlukana kwe-adipocyte kwaye zehlisa umngcipheko wokutyeba ngokulawula ukubonakaliswa kweeproteni ezinxulumene ne-metabolism yamafutha. Okwangoku, kwizilingo ngeenkukhu ezibeka amaqanda, i-Artemisia extract iphucule kakhulu amandla e-antioxidant eengqayi zamaqanda kwaye yandisa ubomi bazo beshelufu.
● Impilo yamathumbu kunye nokulawulwa kwezinto eziphilayo
Izicatshulwa zezityalo ziphucula uluntu lweentsholongwane zamathumbu ngokuthintela iintsholongwane eziyingozi nokukhuthaza ukwanda kweeprobiotics. Umzekelo, izicatshulwa ezivela kwizityalo zeCinnamomum zinokunciphisa umsebenzi we-urease kunye ne-uricase, kwaye zinciphise ukukhutshwa kwe-ammonia. Izicatshulwa zeYucca kunye ne-fructooligosaccharides (FOS) zinceda ukulawula ibhalansi yeentsholongwane ezinjeni nakwiikati, zinciphisa ii-metabolites eziyingozi ezifana ne-ammonia kunye ne-histamine. Ukongeza, ii-polysaccharides zezityalo zisebenza njengeziseko zokubilisa iintsholongwane, zivelisa ii-fatty acids ezimfutshane ezikhuthaza ukwanda kweeseli ze-epithelial zamathumbu kwaye ziphucula ukusebenza kakuhle kokufunxwa kwezondlo. Kwizilingo zeengulube, umxube we-carvacrol kunye ne-cinnamaldehyde wandise kakhulu umsebenzi we-pepsin kwaye wehlisa urhudo.
● Ukukhuthaza ukukhula nokuguqulwa kokutya
Izicatshulwa zezityalo zikhuthaza ukukhula kwezilwanyana ngokuphucula ukuncasa kokutya, ukwandisa umsebenzi wee-enzymes zokugaya ukutya kunye nokulawula ukukhutshwa kweehomoni. Umzekelo, i-star anise essential oil inyusa kakhulu ubude be-intestinal villus kunye nokutya okutyiwa zizilwanyana; i-cinnamon extract iyalibazisa izilonda zamathumbu kwaye iphucula ukusetyenziswa kokutya. Kwizifundo eziphathelele kwiikati zezilwanyana zasekhaya, ii-proanthocyanidins zithintela ukwanda kweeseli zamafutha kwaye zinciphisa izinga lamafutha emzimbeni ngokulawula iijini ezinxulumene ne-metabolism yamafutha.
Ukusetyenziswa Okukhethekileyo Kwezicatshulwa Zezityalo Kwimveliso Yesondlo Sezilwanyana
● Ukufuya imfuyo kunye neenkukhu: ubuchwepheshe obuphambili bokuthatha indawo yee-antibiotics
Phantsi kwemvelaphi "yokutya okungenazo ii-antibiotic", izicatshulwa zezityalo ziye zaba yindlela ebalulekileyo kwitekhnoloji yokutshintsha ii-antibiotic. Umzekelo, isicatshulwa samagqabi se-Eucommia ulmoides, esityebileyo kwi-chlorogenic acid kunye ne-Eucommia flavonoids, sinokuthatha indawo yee-antibiotics ukukhuthaza ukukhula kwamantshontsho eehagu; isicatshulwa se-Dandelion sonyusa ukumelana nentsholongwane yesifo saseNewcastle kumantshontsho, sinciphise amazinga okufa. Kwimveliso yenkukhu ebeka amaqanda, izicatshulwa ze-Lonicera japonica kunye nezicatshulwa zeTurmeric zinokunciphisa izinga lamaqanda angenamaqokobhe kwaye ziphucule impilo ye-oviduct. Ukongeza, ii-oyile ezibalulekileyo (ioyile ye-oregano), ii-alkaloids (i-berberine, i-artemisinin, i-sanguinarine) ziphucula impilo yamathumbu ngokusebenzisa imisebenzi ye-antioxidant, i-antibacterial kunye ne-antiparasitic. Izicatshulwa zezityalo ezisusa ubushushu (umz. isicatshulwa se-Scutellaria baicalensis, isicatshulwa se-Honeysuckle) zinokuphucula ngempumelelo ukusebenza kweenkomo ezixinezelekileyo kubushushu.
● Ukutya kwezilwanyana zasekhaya: ulawulo oluchanekileyo lweempawu zempilo
Izicatshulwa zezityalo zibonakalise impembelelo ebalulekileyo ekusombululeni imiba efana nokutyeba kakhulu kunye nokuvuvukala kwamathumbu kwizinja zasekhaya. Isicatshulwa seGinkgo biloba sinokunciphisa ubunzima bomzimba kunye nesantya samafutha emzimbeni kwizinja ezityebileyo. IiProanthocyanidins zithintela ukwanda kweeseli zamafutha ngokulawula iijini ezinxulumene nemetabolism yamafutha. Ukongeza, isicatshulwa seYucca sinokuguqula i-microbiota yamathumbu ezinjeni nakwiikati, sinciphise iimetabolites eziyingozi (ezifana ne-ammonia kunye ne-histamine) kwaye siphucule ivumba lendle. Ukutya kwezilwanyana zasekhaya okanye izidlo ezityiwayo ezineepolyphenols zeti eluhlaza zinokuthintela ukukhula kweebhaktheriya eziyingozi zomlomo, zinciphise i-plaque yamazinyo kunye ne-calculus yamazinyo, kwaye zithintele izifo zomlomo ezifana ne-periodontitis. Izicatshulwa zezityalo ezityebileyo kwiivithamini kunye nee-antioxidants, ezifana nesicatshulwa se-flaxseed, isicatshulwa se-blueberry, kunye ne-lecithin, zibonelela ngesondlo kwiinwele zezilwanyana zasekhaya, zenze zibe thambile kwaye zikhazimle.
● Izilwanyana ezitya inyama kunye nokulima iintlanzi: amasimi asetyenziswayo asakhulayo
Kwizilwanyana ezitya imfuyo, izicatshulwa zezityalo (ezifana ne-yucca saponins) zinokulawula ukuvutshelwa kwe-rumen kwaye ziphucule ukusetyenziswa kwe-nitrogen. Kwizilwanyana zasemanzini, izicatshulwa zamagqabi e-Eucommia ulmoides zinokuphucula ukhuseleko lweentlanzi kwaye zinciphise amazinga okufa.
Imingeni yoSetyenziso kunye namaqhinga okuphucula
● Iingxaki zobugcisa ezikhoyo
Ukutyeba: Iioyile ezibalulekileyo (umz. ioyile ye-oregano) zinokunciphisa ukutya kwezilwanyana zasekhaya.
Ukungahambelani: Iidosi eziphezulu zeetannins zithintela umsebenzi weprotease kwaye zinciphisa ukugaywa kweproteni.
● Izisombululo kunye nokuthambekela kophuhliso
I-Microencapsulation: I-Beta-cyclodextrin encapsulation ye-thymol inciphisa ilahleko eziguquguqukayo nge-70% kwaye yandisa ixesha lokusebenza.
Ifomula Yesayensi: Ukudibana kwe-curcumin kunye ne-piperine kwandisa ukufumaneka kwezinto eziphilayo ngokuphindwe ka-20.
Izicatshulwa zezityalo zinamathuba amaninzi okusetyenziswa kunye namathuba amakhulu ophuhliso kwicandelo lokutya kwezilwanyana kunye nokhathalelo lwempilo. Ngophando oluqhubekayo kunye nokusebenza, ubuchwepheshe bazo bokusetyenziswa buya kuphuculwa rhoqo ukubonelela ngenkxaso enamandla yokukhuthaza uphuhliso oluluhlaza noluzinzileyo lokufuya izilwanyana kunye nokuvelisa ukutya okukhuselekileyo nokusemgangathweni okuvela kwizilwanyana. Kwixesha elizayo, izicatshulwa zezityalo kulindeleke ukuba zidlale indima ebaluleke ngakumbi kwishishini lokufuya izilwanyana.