Isicatshulwa seMacleaya cordata
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Ulwazi oluSisiseko
Igama lemveliso: I-Berberine hydrochloride
Inkangeleko: Umgubo otyheli wekristale
Ifomula yemolekyuli: C20H18ClNO4
Ubunzima beemolekyuli: 372.822
Inombolo ye-CAS: [633-65-8]
Ukupakisha okuqhelekileyo: 25kg/idrama
Ukunyibilika: Inyibilika lula emanzini abilayo, inyibilika kancinci emanzini abandayo, kwaye ayinyibiliki phantse kwi-ethanol ebandayo, i-chloroform, kunye ne-ether.
Umgangatho woMgangatho: I-CP2020, i-JP, Yenzelwe umthengi
Izithako eziphambili ezisebenzayo
Izithako ezisebenzayo zeBoluohui extract zii-benzophenanthridine alkaloids, apho iSanguinarine kunye neChelerythrine zinomlinganiselo ophezulu, zibanga i-50% ~ 80% yee-alkaloids zizonke.
Igama le-alkaloid | Ifomula yemolekyuli | I-CAS | Ubungakanani boMxholo | Umsebenzi ophambili |
I-Sanguinarine | C₂₀H₁₄HAYI₄⁺ | 2447-54-3 | 30%~50% | I-antibacterial kunye ne-antiparasitic |
I-Chelerythrine | C₂₁H₁₈HAYI₄⁺ | 34316-15-9 | 20%~40% | Ilwa nokudumba kunye nokulwa nomhlaza |
Iprotopine | C₂₀H₁₉HAYI₅ | 130-86-9 | 5%~10% | I-Analgesia kunye ne-anti-inflammatory |
I-Allocryptopine | C₂₁H₂₃HAYI₅ | 485-91-6 | 3%~8% | i-antiarrhythmic |
Iziphumo ze-Pharmacological kunye nokusebenza kakuhle
1. Iintsholongwane ezibanzi
Indlela yokusebenza: itshabalalisa i-membrane yeseli yebhaktheriya, iphazamisana nokuphindaphinda kwe-DNA
Iintsholongwane ezinobuzaza:
Iintsholongwane zeGram-positive (Staphylococcus aureus, Streptococcus)
Iifungi (iiCandida albicans)
Iintsholongwane (i-coccidiosis, iintshulube ezingqukuva)
I-spirochetes ye-porcine dysentery (ukuthintela kunye nokunyanga i-hagu dysentery)
2. Ulawulo lokulwa nokudumba kunye nomzimba
Ukuthintela indlela ye-NF-κ B kunye nokunciphisa ukukhululwa kwezinto ezibangela ukudumba ezifana ne-TNF-α kunye ne-IL-6
3. Impembelelo yokukhuthaza ukukhula (yokusetyenziswa kwezilwanyana)
Ukuphucula impilo yamathumbu emfuyo kunye neenkukhu, ukwandisa izinga lokuguqulwa kokutya (ukutshintsha amayeza okubulala iintsholongwane)
4. Umsebenzi Wokulwa Nethumba (Inqanaba Lophando)
Ukukhuthaza i-apoptosis yeeseli zethumba (ngokusebenzisa indlela yeCaspase-3 nge-sanguinarine)
IiNdawo zeSicelo Ubuninzi obuluhlaza
1. Amayeza ezilwanyana kunye nezongezo zokutya
Ukutya kwehagu/kwenkukhu (0.5-2g/kg) ukuthintela nokunyanga isifo sorhudo kunye ne-coccidiosis
Ukulima amachibi (ukuthintela iVibrio, ukuthintela kunye nonyango lwe-white stool syndrome kwi-shrimp)
2. Izibulali-zinambuzane
Izibulali-zinambuzane zendalo ezisekelwe kwizityalo (zokulawula ii-aphids kunye neentshulube zesigcawu)
3. Uphando noPhuhliso lweMithi
Amalungiselelo okulwa neentsholongwane ngomlomo (intlama yamazinyo, isihlambi somlomo)
Iikhompawundi zelothe zamayeza okulwa nomhlaza
4. Izinto zokuthambisa
Izithako zokususa amaqhakuva (ezithintela i-Propionibacterium acnes)
Izisombululo zeSicelo
Idosi Ecetyiswayo
● Isongezelelo sokutya: 50-150g/ton yemfuyo, 100-200g/ton yezolimo zasemanzini
● Ukusetyenziswa kwezibulali-zinambuzane: Ukuxutywa kwe-500-1000x yokutshiza
Ukulumkela
※ Ukufaka amayeza kufuna ulwalathiso lobuchwephesha
※ Kuphephe ukudibana nezinyibilikisi ezinamandla
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