Izinto ekufuneka ziqwalaselwe ngamayeza emveli aseTshayina (i-TCM)
| Icala eliPhambili | Izinto ekufuneka ziqwalaselwe | Amanyathelo oLawulo loMngcipheko |
| Unyango lwangaphambi kweHerbs | Ubungakanani bokufuma, ubungakanani befayibha/oyile | Lawula ukufuma (ngesiqhelo ≤10%); tyumza ii-herbs ezine-fibrous okanye ezinamafutha ngaphambi kokuba kuyimfuneko |
| Ukukhetha Izixhobo | Iimpawu zezityalo (ubulukhuni, ukutyeba, njl.njl.) | Sebenzisa ii-hammer mills kwi-brittle herbs, ii-shear okanye ii-turbo mills kwi-fibrous herbs |
| Ulawulo lobushushu | Ukuveliswa kobushushu okukhokelela ekulahlekelweni kweekhompawundi ezisebenzayo | Ukutyumza ngobushushu obuphantsi (umz., ukupholisa amanzi), ukusebenza okukhawulezileyo; ukugaywa kwe-cryogenic (i-nitrogen engamanzi) kwiimifuno ezibuthathaka kubushushu |
| Iimfuneko zoBuchule | Imigangatho yobukhulu bamasuntswana kwiindlela ezahlukeneyo zokusetyenziswa (umz., iipilisi, iipowders, izicatshulwa) | Lungisa i-seeve mesh (ngesiqhelo i-80–200 mesh) ngokusekelwe kwiimfuno zenkqubo; thintela ukutyumza kakhulu okuchaphazela ukusebenza kakuhle |
| Ukuthintela uthuli kunye nokuqhuma | Iingozi ezinokutsha/eziqhumayo (umz., isitatshi, iioyile eziguquguqukayo) | Sebenzisa iimoto ezithintela ukuqhuma, ukhuseleko lwegesi engasebenziyo, ukususwa kothuli, kunye namanyathelo okulwa nokunganyakazi |
| Ungcoliseko lweMicrobial | Iintsholongwane ezivela kwimifuno okanye kwindawo esingqongileyo | Sebenza kwiindawo ezicocekileyo; faka imitha okanye ukubulala iintsholongwane ukuba kuyimfuneko |
| Ulawulo lokuNgcoliswa kweNsimbi | Izicucu zesinyithi ezivela kwiimpahla ezinxitywayo | Ukwahlulwa kwemagnethi, ukuhlolwa rhoqo kweesivi/iiblade; beka phambili izixhobo zentsimbi engagqwaliyo |
| Ukufana kweCandelo | Ukwahlulwa kwezakhi ngenxa yokwahluka kobuninzi kwiimifuno ezixutyiweyo | Ukutyumza okunezigaba ezininzi + ukuxuba, okanye sebenzisa itekhnoloji yokudibanisa i-composite |
| Ungcoliseko oluNxulumeneyo | Intsalela yemikhondo phakathi kwemifuno eyahlukeneyo | Iinkqubo zokucoca ezingqongqo, ukufaka imibala kwikhowudi, okanye imigca yemveliso enikezelweyo |
| Ukugcinwa kweeCompounds eziguquguqukayo | Iimifuno ezinevumba elimnandi (umz., i-mint, i-borneol) | Ukutyumza okuvaliweyo, ukucutshungulwa ngokukhawuleza kubushushu obuphantsi ukuze kuncitshiswe ukuvezwa |
Amanqaku abalulekileyo oLawulo lweNkqubo ngexesha lokuveliswa kweSodium deoxycholate
| Inyathelo | Iiparameter zoLawulo | Ukunciphisa umngcipheko |
| I-Hydrolysis | Uxinzelelo lwe-NaOH, ubushushu, ixesha | Kuphephe ukukhupha i-hydrolysis engaphezulu ukuze kuthintelwe ukungcola |
| Ukuna kwe-asidi | i-pH (ngokungqongqo yi-3-4), izinga lokuphola | Thintela ukuhlanganiswa kwe-emulsification okanye ukuvalelwa kokungcola kwiindawo ezimanzi |
| Ukukhupha ioksijini | Umsebenzi weCatalyst, idosi yoxinzelelo lwe-H₂/yokunciphisa iarhente | Isiphelo sempendulo yeMonitor (TLC/HPLC) |
| Ukuphinda kusetyenziswe icrystallization | Umlinganiselo we-solvent, ubushushu bokususa umbala | Sebenzisa ikhabhoni esebenzayo yodidi lwamayeza ukuze uphephe iintsalela zesinyithi esinzima |
| Ukwakheka kwetyuwa | Ulawulo lwe-pH oluchanekileyo (8-9) | Nqanda ukwenziwa kwe-alkalization eninzi kwindawo leyo ekhokelela ekuwohlokeni |
| Ukomisa | Ubushushu ≤60℃, inqanaba le-vacuum | Kuphephe ukubola okanye ukuxinana kwezinto ezibuthathaka kubushushu |
Sisazimisele ngokuqinileyo kwindlela eqhutywa kabini edibanisa iinkqubo zolawulo lwe-GMP kunye ne-ISO, sidibanisa ukhuseleko, ukhuseleko lokusingqongileyo kunye nokuvelisa izinto ezintsha njengemigaqo yethu esisiseko. Oku kubonisa indlela yethu yesayensi yokuphucula ukhuphiswano oluphambili kunye nokufezekisa uphuhliso oluzinzileyo.
Uluhlu lweZixhobo zeMveliso eziNgaphelelanga:
Itanki yokukhupha, ikholamu yokukhupha, i-centrifuge, i-concentrator, inkqubo yokukhupha i-counter-current, i-homogenizer, i-UHT sterilizer, i-spray dryer, i-microwave dryer, i-mixer, njl.njl.
Dibana no
Ukuba ufuna ulwazi oluthe kratya malunga neenkqubo zemveliso kunye neenkonzo ezenzelwe wena, nceda uzive ukhululekile ukuqhagamshelana neqela lethu leengcali nangaliphi na ixesha.